Novel genetic environment of plasmid-mediated quinolone resistance gene qnrB2 in Salmonella Bredeney from poultry

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Novel genetic environment of qnrB2 associated with TEM-1 and SHV-12 on pB1004, an IncHI2 plasmid, in Salmonella Bredeney BB1047 from Spain.

The presence of the qnrB2 gene in animal isolates and zoo-notic pathogens opens the possibility that genetic exchange and plasmid acquisition of the qnrB2 gene could occur in the faecal flora of the animals. Interestingly, p137.25 belongs to the IncN plasmid family that is able to replicate in different enterobacter-ial strains, but also seems prevalent in faecal flora from animals. In fact, a ...

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Plasmid-mediated Quinolone Resistance in Salmonella enterica, United Kingdom

1. World Health Organization. Global strategy for containment of antimicrobial resistance [cited 2006 Nov 10]. Geneva: The Organization; 2001. Available from http://www.who.int/drugresistance/en 2. Bartoloni A, Pallecchi L, Benedetti M, Fernandez C, Vallejos Y, Guzman E, et al. Multidrug-resistant commensal Escherichia coli in children, Peru and Bolivia. Emerg Infect Dis. 2006;12:907–13. 3. Pal...

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Plasmid-mediated quinolone resistance determinants in Salmonella spp. isolates from reptiles in Germany.

Escherichia coli isolates expressing plasmid-mediated quinolone resistance and expanded-spectrum b-lactamase. Antimicrob Agents Chemother 2006; 50: 1525–7. 9 Strahilevitz J, Engelstein D, Adler A et al. Changes in qnr prevalence and fluoroquinolone resistance in clinical isolates of Klebsiella pneumoniae and Enterobacter spp. collected from 1990 to 2005. Antimicrob Agents Chemother 2007; 51: 30...

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Plasmid-mediated quinolone resistance in Salmonella isolated from patients with overseas travelers' diarrhea in Japan.

Twenty-eight of the 302 Salmonella strains isolated from patients with overseas travelers' diarrhea who were examined at Kansai Airport Department Station during the 6-year period between 2001 and 2007 showed decreased susceptibility to both nalidixic acid (NA) and ciprofloxacin (CPFX) (MIC of NA, 16-64 microg/mL; MIC of CPFX, 0.064-2.0 microg/mL). These 28 strains revealed no variations in the...

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qnrB, another plasmid-mediated gene for quinolone resistance.

A novel plasmid-mediated quinolone resistance gene, qnrB, has been discovered in a plasmid encoding the CTX-M-15 beta-lactamase from a Klebsiella pneumoniae strain isolated in South India. It has less than 40% amino acid identity with the original qnr (now qnrA) gene or with the recently described qnrS but, like them, codes for a protein belonging to the pentapeptide repeat family. Strains with...

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ژورنال

عنوان ژورنال: Journal of Antimicrobial Chemotherapy

سال: 2009

ISSN: 0305-7453,1460-2091

DOI: 10.1093/jac/dkp356